Reumofan and Reumofan Plus are manufactured by the Mexican company Riger Naturals. The supplements are marketed as muscle and arthritis pain relievers.
The FDA found that Reumofan Plus contained Diclofenac Sodium, an anti-inflammatory drug that increases the risk of heart attack and other complications in the stomach and intestines. In Reumofan Plus, FDA laboratories also discovered methocarbamol, a muscle relaxant and dexamethasone, a drug that suppresses the immune system.
The FDA has also received reports of several mild and serious side effects, including liver injury, uncontrolled sugar levels, weight gain, swelling, cramping in the legs and kidney dysfunction (adrenal suppression).
According to the statement issued by the FDA, individuals currently taking Reumofan Plus or recently stopped taking Reumofan Plus should immediately consult a healthcare professional. The drugs in Reumofan Plus may interact with other medications.
The Mexican Ministry of Health has ordered a recall of Reumofan Plus.
For information about integrative therapies with evidence of benefit for pain relief, please visit Natural Standard's Comparative Effectiveness Database.