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August 27, 2013

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All I can think of is exam weeks, where I would of used something like this to help with sleep and other various attributes of Ginseng. Of course, long term studies help with understanding the long term effects but if it helps with a stressful work week then why not?

Interesting and unexpected. Having trouble staying asleep myself, I may give this a try even before additional evidence is compiled. Now, to just find a reputable source . . .

There are so many factors that influence sleep quality that I'm hesitant to read into this much. Might be worth a shot for otherwise healthy people who have trouble sleeping though.

Another thing to consider with Ginseng supplementation are drug interactions. Many people who have trouble sleeping may take concurrent medications, such as antidepressants or sleep medications or anti-anxiety medications. All of these have the potential to interact with ginseng. Therefore, patients who plan on initiating a ginseng regimen should make their healthcare provider aware.

This is an interesting property of ginseng I was not previously aware of. It seems plausible based on the mechanism of action of ginseng (reduction in GABAAergic systems) would help with mental performance and memory, but it seems almost paradoxical that this would enable better sleep. I am wondering if the ginseng is taken during the day it allows better “bounce-back” (so to speak) of the GABAergic systems in the brain at night to promote more stable sleep and REM patterns.

I have problem staying asleep lately. I wake up at exactly 3:36am each morning. I wonder how gingseng works with sleep. Where can I get ginseng? I am willing to try anyhting.

Although this study concludes positive results it is merely an experimental type pilot study with no causality derived from its findings. There is no mention of randomization, placebo, blinding and very small sample size. As a future pharmacist this would not be something I would recommend to patient until clinical evidence comes out to warrant the claims made by this study.

Since I have trouble sleeping on many occasions this article proved to be very valuable. I know when I am stressed out I tend to have a harder time falling asleep and staying asleep. I wonder if ginseng’s ability to reduce stress is the mechanism behind its ability to improve sleep quality. I believe that a larger patient population and longer time frame would be necessary to see if this result is still present

This a pertinent topic, as insomnia and sleep disturbance trouble millions of people every year. What I find particularly intriguing about this evidence for red ginseng is that it doesn't just help you get to sleep, it makes you sleep better. Essentially all the current FDA approved sleeping medications available have been shown to potentially decrease sleep quality even though sleep latency is decreased. If red ginseng truly does increase sleep quality, it would be a breakthrough in the insomnia market!

I agree with Austin there was no mention of any randomization or control placebo to compare results to in the study abstract. It calls to question the validity of the study. Austin also makes another valid point that by pulling volunteers away from their natural sleep environment it may affect their normal sleep cycle and leads to unaccounted variables.

I think it's interesting that ginseng may reduce total wake time considering products like Pepsi Max and other energy drinks incorporate ginseng into their product which is a natural stimulant to help increase alertness.

Whoa! Exactly the opposite of what I would have expected, with the stimulant effects of ginseng. Mind. Blown. I wonder if we should do this kind of research with other stimulants? Maybe caffeine is the just fall guy for insomniacs.

While interesting, I would like to see this trial done with blinding and randomization. The abstract here makes no mention of either of these steps so the results here do not take the placebo effect into account. It also sounds like that the volunteers involved were kept in-patient for observation during their sleep which may affect their sleep behavior and restfulness.

An interesting study, I would be interested to see if the results would be consistently the same if the study included women and was conducted for a longer period of time. Also, I think it would be beneficial to perform the PSG studies during the time in which the patient is taking the ginseng to see if the patient's sleep cycle is gradually changing from the ginseng and if different doses have different responses in the architecture of the individual's sleep patterns.

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