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November 25, 2013

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This is very interesting since calcium and Vitamin D are the go-to drugs for over-the-counter treatment and prevention of osteoporosis and osteopenia. I am interested to see if future studies support this finding. Also, it makes sense that DHEA supplementation would increase bone density. Since your body's supply of DHEA peaks at 20-25 and declines with age, supplementation would be necessary in post menopausal women. Anybody heard about any clinical with DHEA and the prevention/treatment of osteoporosis?

Strontium ranelate is only available in Europe and is an orally active drug consisting of two atoms of stable strontium and an organic moiety (ranelic acid). It’s mechanism of action in human is still unknown, but in animal studies, it appears to inhibit bone resorption. According to clinical trials trontium ranelate is effective for reducing the risk of vertebral fractures and, to a lesser extent, non-vertebral fractures. Some of the common adverse effects are diarrhea, venous thromboembolism, and pulmonary embolism.

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