Health & Wellness

July 14, 2008

Natural Medicine for TMJ Disorders

Tmj Traditional Chinese medicine and naturopathic medicine may offer effective treatments for temporomandibular joint (TMJ) disorders.

TMJ disorders are a group of medical conditions that cause the jaw joint to be sore and painful. This joint connects the lower jaw, called the mandible, to the temporal bone of the skull, which is located in front of the ear on both sides of the head. The TMJ allows the jaw to move up and down and side to side. These movements are important for many functions, including talking, chewing food and yawning.

TMJ disorders are often divided into three categories: myofascial pain, internal derangement and arthritis. Myofascial pain is the most common TMJ disorder. It occurs when the muscles that control the jaw are sore or tender, and the cause remains unknown. Internal derangement of the joint occurs when the joint becomes injured by a blow to the jaw. The injury may dislocate the jaw or displace a disc. Internal derangement may also damage the rounded ends of the lower jaw (called condyles). Arthritis, which causes inflammation and swelling of joints, is another form of TMJ. A patient may have one or more of these TMJ disorders, which may affect one or both sides of the jaw.

The exact number of people who have TMJ disorders remains unknown. However, as many as 10 million Americans experience symptoms related to TMJ disorders, according to the National institute of Dental and Craniofacial Research (NIDCR). For unknown reasons, these disorders occur more often in women than men. In general, TMJ disorders are most likely to develop in individuals who are 20-40 years old.

Researchers from the University of Arizona, Tucson, AZ, assessed the feasibility and acceptability of studying whole systems of traditional Chinese medicine and naturopathic medicine in the treatment of temporomandibular disorders (also abbreviated TMD) and investigated whether there is indication to support further research.

The study compared whole system traditional Chinese medicine and naturopathic medicine to state-of-the-art specialty care in 160 women 25-55 years of age attending a Kaiser Permanente Northwest TMD specialty clinic.

The intervention protocols were designed to model the individually tailored type of community care offered in alternative medicine practices in Portland and in the Kaiser Permanente Northwest TMD clinic. The protocols enhanced similarities among practitioners within each system and permitted full descriptions of the treatments provided.

The study found that traditional Chinese medicine and naturopathic medicine demonstrated significantly greater in-treatment reductions for worst facial pain compared to specialty care and at three months post-treatment. Additionally, traditional Chinese medicine provided significantly greater decreases in average pain than specialty care; naturopathic medicine provided significantly greater decreases than specialty care or traditional Chinese medicine in TMD-related psychosocial interference.

The authors concluded that these alternative medicine approaches resulted in significantly greater reductions of pain and psychosocial interference than specialty care. They suggested that further research on the potential benefits of traditional whole systems of medicine for TMD may be warranted.

Several other medical problems, including sleep disturbances, chronic fatigue syndrome, and a painful condition that affects the muscles and other soft tissues in the body (called fibromyalgia), have been associated with TMJ disorders. However, it is unknown if these health problems share a common cause with TMJ disorders.

Because the cause of many temporomandibular joint (TMJ) disorders remains unknown, there is no known method of prevention.

Music Therapy for Depression and Anxiety

Music Music therapy may improve depression, anxiety and relationships in psychiatric patients, a new study reports.

Music is an ancient tool of healing that was recognized in the writings of the Greek philosophers Pythagoras, Aristotle and Plato. The modern discipline of music therapy began early in the 20th Century with community musicians visiting veterans' hospitals around the country to play for those traumatized by war. The positive response prompted many hospitals to hire musicians to play for their patients.

Studies suggest that music may be used to influence physical, emotional, cognitive and social well-being and improve quality of life for healthy people, as well as those who are disabled or ill. It may involve either listening to or performing music, with or without the presence of a music therapist.

Music therapists are professionally trained to design specialized applications of music according to an individual's needs using improvisation, receptive listening, song writing, lyric discussion, imagery, performance or learning through music. They work in psychiatric hospitals, prisons, rehabilitative facilities, medical hospitals, outpatient clinics, day treatment centers, agencies serving developmentally disabled persons, community mental health centers, drug and alcohol programs, senior centers, nursing homes, hospice programs, correctional facilities, halfway houses, schools and private practices.

Infants, children, adolescents, adults, the elderly and even animals can all potentially benefit from music therapy. Research supports all forms of music as having therapeutic effects, although music from one's own culture may be most effective. Types of music differ in the types of neurological stimulation they evoke. For example, classical music has been found to soothe and comfort the listener, while rock music may be unsettling and cause distress.

Researchers from the Graduate School of Art Therapy, Daejeon University, Daejeon, South Korea, tested whether group music therapy is effective for improving depression, anxiety and relationships in 26 patients allocated to either a music intervention group or a routine care group.

The music intervention group received 60 minutes of music intervention for 15 sessions (one or two times weekly).

The study found that after 15 sessions, the music intervention group showed significant improvements in depression, anxiety and relationships compared with the control group.

The authors concluded that despite the positive results, objective and replicable measures are required from a randomized controlled trial with a larger sample size and an active comparable control.

There is evidence that music that reflects the listener's personal preference is more likely to have desired effects. It is possible that music through headphones during medical procedures could interfere with the patient's cooperation with the procedures. Further research is needed in this area.

Ethnicity, Food Choices and Health

Food_mexican Two new studies examined how ethnicity may influence dietary habits, which may in turn affect health. Obesity rates are higher and more dramatic in African American and Hispanic populations compared to Caucasians and researchers attribute this to socioeconomic and ethnic disparities.

A study by the RAND Corporation in Pittsburgh, PA, examined the associations between fruit and vegetable intake and neighborhood socioeconomic status. The researchers analyzed whether socioeconomic status explains ethnic differences in food intake, and explored the extent to which socioeconomic status has differential effects by ethnicity of U.S. adults.

The researchers found that socioeconomic status was positively associated with fruit and vegetable intake: a higher socioeconomic status was associated with the consumption of nearly two additional servings of fruit and vegetables per week.

The authors concluded that socioeconomic status explained some of the African American-Caucasian disparity in fruit and vegetable intake and was differentially associated with fruit and vegetable intake among Caucasians, African Americans and Mexican Americans.

In a related study by the Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, researchers observed that dairy consumption and associated nutrients may be protective against some of the components of the metabolic syndrome. The metabolic syndrome is a group of risk factors of a metabolic origin that increase the risk of diabetes, coronary heart disease, stroke and peripheral vascular disease; it is also called syndrome X.

The study examined the association between the consumption of a variety of dairy products and their related nutrients with obesity, central obesity and metabolic syndrome and it attempted to explain some of the ethnic differences in metabolic outcomes through dairy consumption using national data.

Indicators of obesity, central obesity and metabolic syndrome among U.S. adults were constructed from the National Health and Nutrition Examination Survey 1999-2004 data, including direct anthropometric assessments, blood pressure and laboratory tests. Sample sizes ranged from 4,519 for metabolic syndrome to 14,618 for obesity.

The study found a significant inverse association between metabolic syndrome and the intake of whole milk, yogurt, calcium and magnesium. Using structural equation models, ethnic differences in some metabolic syndrome outcomes, such as body mass index and systolic blood pressure, were partly explained by variations in dairy-related nutrients.

The authors concluded that dairy products may have differential associations with metabolic disorders, including obesity. Ethnic differences in dairy consumption may explain in part the ethnic disparities in metabolic disorders in the U.S. population.

For more information on nutrition and health, please visit Natural Standard’s Health & Wellness and Nutrition databases.

June 06, 2008

Chiropractors and CAM

Chiropratic A new study surveyed chiropractic practitioners in the United States to determine whether or not they identified themselves in the complementary and alternative medicine (CAM) category.

Researchers from Cleveland Chiropractic College-Kansas City, Kansas City, MO, explained that chiropractic care in the United States exhibits characteristics of both mainstream healthcare and CAM.

The study investigated the opinions of a sample of chiropractic faculty and practitioners on the appropriate classification of their profession, in terms of CAM versus mainstream.

The faculty sample consisted of all faculty members holding Doctor of Chiropractic (D.C.) degrees at four chiropractic colleges: two in the Midwest and two in southern California. The practitioner sample consisted of all 108 participants, located in 32 states in the United States, in a chiropractic practice-based research network.

In the study, 191 D.C. faculty were invited to participate, and 71 (37 percent) completed the survey. Of the 108 practicing D.C.s invited to participate, 61 (57 percent) completed the survey.

The researchers found that of the total sample of 132, 69 percent did not agree that chiropractic should be categorized as CAM. Rather, 27 percent thought that chiropractors should be classified as integrative medicine, and 20 percent of practitioners and six percent of faculty considered chiropractic mainstream medicine.

The authors concluded that the majority of the chiropractors in this sample rejected being characterized as CAM practitioners, showing some preference for the term integrative medicine.

For more information about chiropractic care, please visit Natural Standard’s Health & Wellness database.

May 23, 2008

Traditional Chinese Medicine and Infertility

Pregnant_couple A new review noted the growing use of traditional Chinese medicine in the treatment of infertility.

Researchers explained that recent studies demonstrated that traditional Chinese medicine could regulate the gonadotropin-releasing hormone to induce ovulation and improve the uterus blood flow and menstrual changes of the endometrium. In addition, it also has an impact on patients with infertility resulting from polycystic ovarian syndrome, anxiety, stress and immunological disorders.

Although study design with adequate sample size and appropriate control for the use of traditional Chinese medicine is not sufficient, the effective studies have already indicated the necessity to explore the possible mechanisms, including effective dose, side effects and toxicity of traditional Chinese medicine, in the treatment of infertility.

The authors concluded that the growing popularity of traditional Chinese medicine used alone or in combination with Western medicine highlights the need to examine the pros and cons of both Western and traditional Chinese medicine approaches.

They suggested integrating the principle and knowledge from well-characterized approaches and quality control of both traditional Chinese medicine and Western medical approaches.

For more information about traditional Chinese medicine, please visit Natural Standard’s Health & Wellness database.

May 16, 2008

Psychotherapy for Fibromyalgia

Psychotherapy Various types of psychotherapy, such as cognitive and behavioral therapy and guided imagery, may help treat patients with fibromyalgia. Fibromyalgia is characterized by chronic, widespread pain in the muscles and soft tissues surrounding the joints, and it is accompanied by fatigue.

Researchers from the University of Heidelberg in Germany developed a guideline for the treatment and diagnostic procedures in fibromyalgia syndrome in cooperation with 10 German medical and psychological associations and two patient self-help groups.

A systematic literature search was performed in the Cochrane Collaboration Reviews (1993-12/2006), Medline (1980-12/2006), PsychInfo (1966-12/2006) and Scopus (1980-12/2006). Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine.

Grading of the strengths of recommendations was done according to the German program for disease management guidelines. Standardized procedures to reach a consensus on recommendations were used.

The study found that cognitive and operant behavioral therapy is strongly recommended and guided imagery/hypnotherapy and written emotional disclosure are recommended.

The authors concluded that psychotherapeutic programs tailored to fibromyalgia subgroups should be developed and tested.

For more information about fibromyalgia, please visit Natural Standard’s Medical Conditions database.

May 08, 2008

Healthy Marriage

Wedding A new study supports the growing evidence that healthy marriages equal healthier men and women.

Researchers from Mayo Clinic, in Rochester, MN, investigated whether marital status and self-assessed mental health are independent risk factors for poor self-rated overall health among female primary care patients.

The cross-sectional survey of family medicine patients treated in a clinic in rural Minnesota included 723 women. Self-ratings of mental health, demographics and symptoms were used to predict self-rated overall health.

The study found that women who were single, divorced or otherwise not married or widowed had lower odds of good self-rated overall health compared with married women. Women who were 65 years of age and over, women who rated themselves as depressed and women who reported more physical symptoms also were less likely to have good health compared with younger women, women who did not feel depressed and women with fewer physical symptoms, respectively.

Education was not independently related to health in this sample. Worry was related to health in the univariate analysis but not after controlling for self-assessed depression.

The study authors concluded that in order to improve overall health among rural women seen in primary care settings, special attention may need to be directed at women who are single, are older, report more physical symptoms and feel depressed. They suggested that programs include self-help materials, support groups and counseling services addressing social isolation, employment and financial hardship.

This study comes during a time of marriage crisis in America; almost half of all marriages continue to end in divorce. However, couples who stay married report happier and healthier lives.

In an article for Discovery Health, David Popenoe, a professor of sociology at Rutgers University and co-director of the National Marriage Project, dispelled common myths about marriage. Popenoe asserted that recent research suggests that men and women benefit about equally from marriage, although in different ways. Both men and women live longer, happier, healthier and wealthier lives when they are married. Husbands typically gain greater health benefits, while wives gain greater financial advantages.

Other research found that couples with children have a slightly lower rate of divorce than childless couples. Popenoe found that the most common reasons couples give for their long-term marital success are commitment and companionship. He warned that many studies have found that those who live together before marriage have less satisfying marriages and a considerably higher chance of eventually breaking up. And, according to a large-scale national study, married people have both more and better sex than do their unmarried counterparts; they report enjoying it more, both physically and emotionally.

Another recent study of 17 developed nations found that married persons have a significantly higher level of happiness than persons who are not married after controlling for gender, age, education, children, church attendance, financial satisfaction and self-reported health. The authors asserted that "the strength of the association between being married and being happy is remarkably consistent across nations." Marriage boosted financial satisfaction and health; cohabitation, by contrast, did not increase financial satisfaction or perceived health and the boost to happiness from having a live-in lover was only about a quarter of that of being married, stated the researchers.

And finally, the U.S. Department of Health and Human Services: Administration for Children and Families found benefits for children, men, women and communities.

Children and youth who are raised by parents in healthy marriages, compared to unhealthy marriages, are: more likely to attend college, more likely to succeed academically, physically healthier, emotionally healthier, less likely to attempt or commit suicide, less likely to have behavioral problems in school, less likely to be a victim of physical or sexual abuse, less likely to abuse drugs or alcohol, less likely to commit delinquent behaviors, more likely to have a better relationship with their mothers and fathers, less likely to divorce when they get married, less likely to become pregnant as a teenager or impregnate someone, less likely to be sexually active as teenagers, less likely to contract STDs and less likely to be raised in poverty.

Women who are in healthy marriages are: more likely to have a more satisfying relationship, emotionally healthier, physically healthier, wealthier, less likely to be victims of domestic violence, sexual assault or other violent crimes, less likely to attempt or commit suicide, less likely to abuse drugs or alcohol, less likely to contract STDs, less likely to remain or end up in poverty and more likely to have better relationships with their children.

Men who are in healthy marriages, compared to unhealthy marriages, are: more likely to live longer, physically healthier, wealthier, more likely to have increased stability of employment, more likely to have higher wages, emotionally healthier, less likely to abuse drugs or alcohol, more likely to have better relationships with their children, more likely to have a satisfying sexual relationship, less likely to commit violent crimes, less likely to contract STDs and are less likely to attempt or commit suicide.

And lastly, communities with a higher percentage of couples in healthy marriages report the following: higher rates of physically healthy citizens, higher rates of emotionally healthy citizens, higher rates of educated citizens, lower domestic violence rates, lower crime statistics, lower teen age pregnancy rates, lower rates of juvenile delinquency, higher rates of home ownership, lower rates of migration, higher property values and decreased need for social services.

For more information, please visit Natural Standard's Medical Conditions database, specifically the Marital Distress Monograph.

 

Mindfulness and Cognitive-Behavioral Therapy for Stress

798pxnelumbo_nucifera1 Mindfulness-based stress reduction may be more effective than cognitive-behavioral stress reduction, a new study reports.

Mindfulness is an approach in which attention is focused on a physical sensation (such as breath). When thoughts intrude, the individual returns to the focus. Attention is placed on the present moment, rather than on the future or past. This technique may involve a "body scan," in which one focuses on the body from head to feet, concentrating on areas of pain or illness. This is usually performed while lying down. Regular practice is suggested to enhance self-awareness.

Researchers from New Mexico investigated the effects of mindfulness-based stress reduction and cognitive-behavioral stress reduction in 50 subjects. Participants self-selected into mindfulness-based stress reduction (36 participants) or cognitive-behavioral stress reduction (14 participants) courses taught at different times. There were no initial differences between the mindfulness-based stress reduction and cognitive-behavioral stress reduction subjects among demographics, including age, gender, education and income.

Mindfulness-based stress reduction was an eight-week course using meditation, gentle yoga and body-scanning exercises to increase mindfulness. Cognitive-behavioral stress reduction was an eight-week course using cognitive and behavioral techniques to change thinking and reduce distress.

The researchers analyzed perceived stress, depression, psychological well-being, neuroticism, binge eating, energy, pain and mindfulness before and after each course. Weekly meetings for both courses were held in a large room on a university medical center campus.

The study found that mindfulness-based stress reduction subjects improved in all eight outcomes, with all of the differences being significant. Similarly, cognitive-behavioral stress reduction subjects improved in six of eight outcomes, with significant improvements on well-being, perceived stress and depression.

According to the researchers, mindfulness-based stress reduction subjects had better outcomes across all variables, when compared with the cognitive-behavioral stress reduction subjects; particularly, mindfulness-based stress reduction subjects had better outcomes with regard to mindfulness, energy, pain and a trend for binge eating.

The study authors concluded that while mindfulness-based stress reduction and cognitive-behavioral stress reduction may both be effective in reducing perceived stress and depression, mindfulness-based stress reduction may be more effective in increasing mindfulness and energy and reducing pain. The authors recommended that future studies examine the differential effects of cognitive behavioral and mindfulness-based interventions and attempt to explain the reasons for the differences.

For more information on these therapies, please visit Natural Standard's Foods, Herbs & Supplements and Health & Wellness databases.

April 02, 2008

Team Sports for Overweight Children

Teamsports An after-school sports program may be an effective weight control intervention for overweight children, a new study reports.

According to the American Heart Association, about 20 percent of children are overweight.

Researchers from Stanford University, School of Medicine, Stanford, CA, explained that current clinical child obesity treatment programs require substantial resources, are able to serve limited numbers of children, are not available in all communities and have generally demonstrated only modest efficacy.

They hypothesized that an organized after-school team sports program may address neighborhood safety concerns that may keep children indoors. Additionally, the researchers suggested that playing sports, being part of a team, receiving mentoring, modeling and friendship from young adult coaches and having opportunities to demonstrate skills in front of friends and family may be fun and highly motivating for children.

The study evaluated the feasibility, acceptability and efficacy of an after-school team sports program for reducing weight gain in overweight children from low-income families.

In the study, 21 children in grades 4 and 5 with a body mass index at or above the 85th percentile were enrolled in an after-school soccer program or "active placebo" control intervention consisting of an after-school health education program (9 to the soccer intervention and 12 to the health education intervention).

The main outcome measures were: implementation, acceptability, body mass index, physical activity measured using accelerometers, reported television and other screen time, self-esteem, depressive symptoms and weight concerns.

The study found that compared with children receiving health education, children in the soccer group had significant decreases in body mass index scores at three and six months and significant increases in total daily, moderate and vigorous physical activity at three months.

The study authors concluded that an after-school team soccer program for overweight children can be a feasible, acceptable and efficacious intervention for weight control.

Integrative therapies that have been studied in the treatment of obesity with strong or good scientific evidence include ephedra, 5-HTP, the Atkins diet, DHEA and psychotherapy. It is important to note that most of these therapies have been studied in adults, not children, and individuals should consult with a qualified healthcare professional before beginning any weight loss plan.

Ephedra contains the chemical ephedrine, which appears to cause weight loss when used in combination with caffeine, based on the available scientific evidence. However, even though this herb has been shown to help reduce weight, it is unsafe for humans for this indication. Serious reactions, including heart attack, stroke, seizure and death, have occurred with using ephedra. The U.S. Food and Drug Administration (FDA) has banned sales of ephedra dietary supplements in all states except for Utah.

5-HTP is the precursor for serotonin, the brain chemical associated with sleep, mood, movement, feeding and nervousness. 5-HTP may alter serotonin levels in the brain, which may then reduce eating behaviors and promote weight loss in obese individuals.

The Atkins Diet® is an eating style that radically departs from the U.S. Food and Drug Administration's (FDA) food pyramid. The Atkins Diet® advocates an increased consumption of fats as the primary source of energy while simultaneously restricting the intake of carbohydrates. This limitation is based on the premise that eating carbohydrates results in the excessive secretion of insulin, potentially resulting in increased fat stores. A carbohydrate-restricted diet has been shown to result in weight loss in obese and non-obese individuals. However, patients should consult with a qualified healthcare professional before beginning any new diet.

DHEA (dehydroepiandrosterone) is a hormone that is produced by the adrenal glands. Most human studies investigating the effects of DHEA on weight or fat loss support its use for this purpose.

Psychotherapy is an interactive process between a person and a qualified mental health professional. The patient explores thoughts, feelings and behaviors to help with problem solving. Several studies indicate that people who are overweight or obese may benefit from behavioral and cognitive-behavioral psychotherapy in combination with diet and exercise to lose weight. Use cautiously with serious mental illnesses or some medical conditions because some forms of psychotherapy may stir up strong emotional feelings and expressions.

Integrative therapies with fair negative evidence in the treatment of obesity include acupressure or shiatsu and beta-glucan.

During acupressure, finger pressure is applied to specific acupoints on the body. Preliminary evidence suggests that acupressure may not be effective for weight loss.

Beta-glucan is a fiber that comes from the cell walls of algae, bacteria, fungi, yeast and plants. Short-term use of fermentable fiber or nonfermentable fiber supplements does not appear to promote weight loss. More study is needed to confirm these findings.

Whole Body Vibration for Parkinson’s Disease

Parkinsons Whole body vibration appears to be as effective as conventional physical therapy for treating gait and improving balance in patients with Parkinson's disease.

Parkinson's disease is a movement disorder that is chronic and progressive; symptoms continue and worsen over time. It affects nerve cells in a part of the brain that controls muscle movement.

Parkinson's disease occurs when a group of cells in an area of the brain called the substantia nigra begin to malfunction and die. The cells in the substantia nigra produce a chemical called dopamine. Dopamine is a neurotransmitter, or chemical messenger, which sends information to the parts of the brain that control movement and coordination.

When an individual has Parkinson's disease, his/her dopamine-producing cells begin to die and the amount of dopamine produced in the brain decreases. Messages from the brain telling the body how and when to move are therefore delivered more slowly, leaving a person incapable of initiating and controlling movements in a normal way.

The four primary symptoms of Parkinson's disease are tremor, or trembling in hands, arms, legs, jaw and face; rigidity, or stiffness of the limbs and trunk; bradykinesia, or slowness of movement; and postural instability, or impaired balance and coordination (parkinsonian gait). As these symptoms become more severe, patients may have difficulty walking, talking or completing other simple tasks.

Parkinson's disease usually affects people over the age of 50. There are 1-1.5 million people in the United States living with Parkison's. The disorder occurs in all races but is somewhat more prevalent among Caucasians. Men are affected slightly more often than women.

Researchers from Germany compared the effects of whole body vibration and conventional physiotherapy on levodopa-resistant disturbances of balance and gait in idiopathic Parkinson's disease.

In the study, 27 patients with Parkinson's disease and dopa-resistant imbalance on stable dopamine replacement medication were randomized (intent-to-treat population) to receive whole body vibration (13 patients) or conventional physical therapy (14 patients).

The subjects received 30 sessions (two 15-min sessions a day, 5 days a week) of either whole body vibration on an oscillating platform or conventional balance training including exercises on a tilt board.

Twenty-one patients (per protocol population) completed follow-up (14 men, 7 women; 10 from the whole body vibration group and 11 controls).

The primary measure was the Tinetti Balance Scale score. Secondary clinical ratings included stand-walk-sit test, walking velocity, Unified Parkinson's Disease Rating Scale (section III motor examination) score, performance in the pull test and dynamic posturography.

The study found that the Tinetti score improved from 9.3 to 12.8 points in the whole body vibration group and from 8.3 to 11.7 in the controls. All secondary measures, except posturography, likewise improved at follow-up compared with baseline in both groups.

Quantitative dynamic posturography only improved in patients with whole body vibration and there was no significant change in controls.

The study authors concluded that equilibrium and gait improved in patients with Parkinson's disease receiving both conventional whole body vibration and conventional physical therapy in the setting of a comprehensive rehabilitation program. There was no conclusive evidence for the superior efficacy of whole body vibration compared with conventional balance training.

Integrative therapies with good scientific evidence in the treatment of Parkinson's disease include 5-HTP and music therapy.

5-HTP has been observed to have benefits in some people who have difficulty standing or walking because of cerebral ataxia (failure of part of the brain to regulate body posture and limb movements). Some research shows that 5-HTP may allow individuals with unsteady movements to stand alone without assistance, walk without aid or have improved coordination. Other research shows no benefit. Further research is needed before a conclusion can be drawn.

Music therapy has been reported to improve symptoms in people with Parkinson's disease. Modest improvement in symptoms including motor coordination, speech intelligibility and vocal intensity, bradykinesia (slow movement), emotional functions, activities of daily living and quality of life were seen.

Kava is an integrative therapy with fair negative evidence in the treatment of Parkinson's disease. It has been shown to increase 'off' periods in Parkinson patients taking levodopa and can cause a semicomatose state when given with alprazolam. Therefore, it is not recommended.

Cognitive Behavioral Therapy for Chronic Fatigue Syndrome

Windup_alarm_clock Cognitive behavioral therapy may be an effective treatment option for adolescents with chronic fatigue syndrome, a new study suggests.

Cognitive behavioral therapy is a psychotherapy based on modifying cognitions, assumptions, beliefs and behaviors with the aim of influencing disturbed emotions.

The particular therapeutic techniques vary, but commonly include: keeping a diary of significant events and associated feelings, thoughts and behaviors; questioning and testing cognitions, assumptions, evaluations and beliefs that might be unhelpful and unrealistic; gradually facing activities that may have been avoided; and trying out new ways of behaving and reacting. Relaxation and distraction techniques are also commonly used.

Chronic fatigue syndrome is a disorder that causes extreme fatigue. The condition does not improve with bed rest. The flu-like symptoms associated with the disorder may last for years.

Researchers at the U.S. Centers for Disease Control and Prevention (CDC) identified the disease in 1988. However, the cause remains unknown, and there is currently no method to measure the severity of the condition. Also, since little is known about the disease, there are few treatment options available.

According to the CDC, about one million Americans have chronic fatigue syndrome. This disease affects more Americans than multiple sclerosis, lupus, lung cancer or ovarian cancer.

Researchers from Radboud University, Nijmegen, The Netherlands, assessed the long-term outcome of adolescents with chronic fatigue syndrome who received cognitive behavioral therapy.

A previous randomized, controlled trial of 66 adolescent patients with chronic fatigue syndrome showed that cognitive behavioral therapy was effective in reducing fatigue and improving physical functioning.

Fifty subjects also participated in a follow-up study and received cognitive behavioral therapy for chronic fatigue syndrome (32 formed the cognitive behavioral therapy group in the original trial, and 18 patients received cognitive behavioral therapy after the waiting period). The remaining 16 patients had refused cognitive behavioral therapy after the waiting period.

The main outcome measures were fatigue severity (Checklist Individual Strength), physical functioning (Short-Form General Health Survey) and school attendance. Data were complete for 61 patients at follow-up (cognitive behavioral therapy group: 47 patients; no-treatment group: 14 patients). The mean follow-up time was 2.1 years.

The study found that there was no significant change in fatigue severity between post-treatment and follow-up in the cognitive behavioral therapy group. However, there was a significant (10 percent) further increase in physical functioning and school attendance.

The adolescents in the cognitive behavioral therapy group were significantly less fatigued and less functionally impaired, and had higher school attendance at follow-up than those in the no-treatment group. Fatigue severity of the mother was a significant predictor of the treatment outcome.

The study authors concluded that the positive effects of cognitive behavioral therapy in adolescents with chronic fatigue syndrome are sustained after treatment. Additionally, higher fatigue severity of the mother may impact treatment outcome in adolescent patients.

Integrative therapies with unclear evidence in the prevention or treatment of chronic fatigue syndrome include DHEA, evening primrose oil, folate and liver extract.

The scientific evidence remains unclear regarding the effects of dehydroepiandrosterone (DHEA) supplementation in patients with chronic fatigue syndrome. Better research is necessary before a clear conclusion can be drawn.

Not enough information is available to advise the use of evening primrose oil for symptoms of chronic fatigue syndrome or fatigue following a viral infection.

Some patients with CFS also have decreased folic acid levels. Daily injections of a combination of folic acid, bovine liver extract and vitamin B12 for three weeks were not beneficial for CFS in one study. Folate appears to be well tolerated in recommended doses.

And finally, an injectable solution of bovine liver extract containing folic acid and cyanocobalamin has been studied as a potential treatment of chronic fatigue syndrome. Preliminary study indicates that patients with chronic fatigue syndrome reacted positively to intramuscular bovine liver extract. Additional study is needed to make a firm recommendation.   

March 13, 2008

Magnetic Stimulation for Ringing in the Ears

Ears Daily sessions of repetitive transcranial (through the head) magnetic stimulation may help treat ringing in the ears or tinnitus.

Repetitive transcranial magnetic stimulation was developed by scientists in the 1980s as a tool for neurodiagnosis, nerve fiber study and the development of a functional brain map.

In the late 1980s, scientists started to use repetitive transcranial magnetic stimulation for the treatment of depression. Over time, the use of repetitive transcranial magnetic stimulation has expanded and is currently not only used for the treatment of depression, but also to treat Parkinson's disease, auditory hallucination schizophrenia, migraines, eating disorders, obsessive compulsive disorder and other mood disorders.

Repetitive transcranial magnetic stimulation is a more specific form of magnet therapy. Magnet therapy is the use of magnets to provide health benefits. Repetitive transcranial magnetic stimulation uses a coil rather than a magnet to produce an electrical current and is specifically used on the scalp. Repetitive transcranial magnetic stimulation is a procedure in which electrical activity in the brain is influenced by a pulsed magnetic field generated by brief current pulses through figure-eight coils of wire. These wires are encased in plastic and held close to the scalp. The location of the device allows for stimulation of specific areas of the cortex (the surface of the brain).

Repetitive transcranial magnetic stimulation is non-invasive and requires no anesthesia. Few patients report any serious side effects. Mild side effects include headache and the perception of unwanted noise. These problems are typically treated with acetaminophen (Tylenol®) and ear plugs, respectively.

Researchers from Assiut University Hospital, Assiut, Egypt, compared the effects of different frequencies of repetitive transcranial magnetic stimulation and sham stimulation given daily over the left temporoparietal cortex for two weeks on 66 patients with chronic tinnitus randomly divided into four treatment groups.

Patients were assessed using the Tinnitus Handicap Inventory, self-ratings of symptoms and audiometric measures of residual inhibition before, immediately after two weeks' treatment and monthly thereafter for four consecutive months.

There were no significant differences in measures between the four groups of patients at the beginning of the study.

The study found that real repetitive transcranial magnetic stimulation produced greater improvement than sham. However, there was no significant difference between the responses to different frequencies of repetitive transcranial magnetic stimulation. The response to repetitive transcranial magnetic stimulation depended on the duration of tinnitus; patients who had tinnitus for the longest period of time were the least likely to respond to treatment.

The study authors concluded that daily sessions of repetitive transcranial magnetic stimulation over the temporoparietal cortex may be a useful potential treatment for tinnitus.

Other integrative therapies studied for the treatment of tinnitus with unclear or conflicting evidence include ginkgo, hypnotherapy, hypnosis, physical therapy, relaxation therapy and zinc.

For more information on repetitive transcranial magnetic stimulation, please visit Natural Standard's Health & Wellness database.  

February 22, 2008

EDTA and Anticancer Drugs

Edta A new study reviewed the effects of EDTA, or ethylene diamine tetraacetic acid, used in the anticancer drug dexrazoxane.

Dexrazoxane hydrochloride (Zinecard®, Pharmacia) is a medication used to protect the heart against the cardiotoxic side effects of anthracycline chemotherapy. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known.

EDTA is a chelating (claw-like) molecule used to remove heavy metals and calcium from the human body. It is one way of treating heavy metal toxicity and atherosclerotic deposits in arteries.

EDTA chelation became well known during the 1950s, when it was proposed as a method to cleanse the blood and blood vessel walls of toxins and minerals. The technique involves infusing EDTA into the blood. The therapy is sometimes given by mouth, and occasionally, other chemicals may be used.

Initially, chelation was used to treat heavy metal poisoning. It was felt by some observers that other benefits occurred in patients receiving this therapy. In current times, chelation practitioners may recommend this treatment for diabetes, for clogged arteries in the heart or legs (peripheral vascular disease) and for numerous other conditions.

Twenty or more sessions may be recommended and can cost several thousand dollars. It has been proposed that treatment with chelation may break down cholesterol plaques in the arteries. Other mechanisms, such as removal of calcium from these plaques and antioxidant properties, have also been suggested. However, there is little scientific evidence to support these theories.

Serious side effects have been associated with chelation therapy, such as dangerously low calcium blood levels, damage to bone marrow that decreases the ability to make new blood cells, kidney damage (with elevated creatinine levels), very low blood pressure, fast heart rate, increased risk of bleeding or blood clots (including interference with the effects of the blood thinning drug warfarin [Coumadin®]), bacterial blood infections, seizures, allergic or immune system reactions, heart rhythm abnormalities and unstable blood sugars. Other side effects may include fever, nausea, vomiting, gastrointestinal upset, excessive thirst, sweating (diaphoresis), headache, decreased thyroid function, fatigue, low white blood cell count (leukopenia) or low blood platelet count (thrombocytopenia). Severe reactions have occurred in which people have stopped breathing. Although deaths have been reported in people receiving chelation, is not clear that chelation therapy was the direct cause.

Researchers from the University of Manitoba in Canada explained that the use of the anthracycline anticancer drugs doxorubicin, daunorubicin, epirubicin and idarubicin sometimes results in accidental extravasation injury and can be a serious complication of their use.

They concluded that dexrazoxane has been shown in two clinical studies and in several case reports to be highly efficacious in preventing anthracycline-induced extravasation injury. Dexrazoxane likely acts by removing iron from the iron-anthracycline complex, thus preventing formation of damaging reactive oxygen species.

February 05, 2008

Behavioral Approach to Fitness

Soldier_running_in_water Behavioral fitness programs proved no more effective than informational pamphlets, a new study reports.

Researchers from the University of Cambridge, UK, explained that declining physical activity is associated with a rising burden of global disease. Efforts to reverse this trend have not been successful.

The study assessed the efficacy of a facilitated behavioral intervention to increase the physical activity of sedentary individuals at familial risk of diabetes. Researchers recruited 365 sedentary adults who had a parental history of type 2 diabetes from either diabetes or family history registers at 20 general practice clinics in the UK.

Participants were randomly assigned to one of two intervention groups or to a comparison group. All participants were sent a brief advice leaflet. One intervention group was offered a one-year behavior-change program to be delivered by trained facilitators in participants' homes, and the other the same program by telephone. The program was designed to alter behavioral determinants, as defined by the theory of planned behavior, and to teach behavioral-change strategies.

The principal outcome at one year was daytime physical activity, which was objectively measured as a ratio to resting energy expenditure. Analysis was by intention to treat.

Out of 365 patients, researchers analyzed primary endpoints for 321 (88 percent) for whom they had data after one-year of follow-up. At one year, the physical-activity ratio of participants who received the intervention, by either delivery route, did not differ from the ratio in those who were given a brief advice leaflet. The physical-activity ratio did not differ between participants who were delivered the intervention face-to-face or by telephone.

The study authors concluded that a facilitated theory-based behavioral intervention was no more effective than an advice leaflet for promotion of physical activity in an at-risk group. The authors suggested that healthcare providers remain cautious about commissioning behavioral programs into individual preventive healthcare services.

For more information on exercise, please visit Natural Standard's Health & Wellness database.

Exercise Breaks at Work

Exerciseatwork Integrating physical activity into the average workday may improve health of employees, a new study reports.

Researchers from UCLA Jonsson Comprehensive Cancer Center in Los Angeles, CA, explained that proactive worksite strategies that change the physical or sociocultural environment(s) to incorporate obligatory physical activity may be necessary to engage sedentary people.

This study analyzed the implementation and evaluation of an intervention, Pausa para tu Salud (Pause for Your Health), that integrated a brief period of group exercise into the workday.

The study tested the effects of integrating daily 10-minute exercise breaks during paid work time during January 2003 through January 2004. A total of 335 Mexican Ministry of Health office workers provided baseline data as a part of routine annual clinical screening examinations.

Baseline mean body mass index and waist circumferences were recorded at 27.8 kilograms/meter squared and 87.6 centimeters for women and 26.6 kilograms/meter squared and 89.7 centimeters for men. Complete data were available for 271 (80.9 percent) employees at one-year follow-up.

The study found that the body mass index decreased by 0.32 kilograms/meter squared and waist circumference by 1.6 centimeters overall. The body mass index decrease, however, was significant only for men. Multivariate analyses revealed a significant decrease in diastolic blood pressure among women.

The study authors concluded that physical activity integrated into a work schedule may result in significant improvements in employee health. The authors suggested that substantive health and organizational benefits may result from integrating brief periods of physical activity into the workday if these findings are replicated in randomized controlled trials in other worksites.

For more information on fitness, please visit Natural Standard's Health & Wellness database.

January 08, 2008

Tips for Weight Loss in the New Year

Treadmill Two new studies offer insight on methods for losing weight as well as the common stumbling blocks of overweight and obese individuals.

In one study, researchers asked the question, "Exercise makes you feel good, but does feeling good make you exercise?"

Researchers from Bowling Green State University in Bowling Green, OH, explained that while exercise-induced mood enhancement has been well documented, the relationship between mood and exercise participation is less understood.

The researchers hypothesized that mood states influence evaluative judgments that could plausibly influence a decision to exercise

The study investigated the influence of morning mood on exercise, exercise intensity/duration on mood enhancement and daily change in mood on exercise days compared with non-exercise days in obese behavioral weight loss program participants. Thirty-six individuals recorded morning, evening and pre-and post-exercise mood, as well as the type, duration and intensity of exercise.

The study found that morning mood was associated with an increased likelihood of exercising, mood ratings were higher following exercise of greater intensity and duration and daily mood enhancement was associated with greater exercise initiation and greater exercise intensity.

The study authors suggested that measuring mood before and after exercise may yield important clinical information that can be used to promote physical activity in obese adults.

A related study examined the dietary practices, dining out behavior and physical activity correlates of weight loss maintenance.

Researchers from the Centers for Disease Control and Prevention (CDC) explained that loss of excess weight can improve blood lipids, insulin sensitivity and blood pressure.

Using the 2004 Styles survey, a mailed survey of U.S. adults aged 18 years or older, the study examined behaviors associated with weight loss maintenance among people who reported trying to lose weight. Data on the number of daily fruit and vegetable servings, minutes per week of physical activity, dining out behavior and confidence in one's ability to engage in behavioral strategies were assessed.

The study found that more men (35.5 percent) than women (27.7 percent) were classified as successful weight loss maintainers. Compared with adults who reported eating at a fast-food restaurant two or more times per week, adults who reported not eating at fast-food restaurants were more successful at weight loss maintenance. Additionally, the study reported that compared with adults who consumed fewer than five fruit and vegetable servings per day and were sedentary, adults who consumed fewer than five fruit and vegetable servings per day and accrued 420 minutes or more per week of physical activity or consumed five or more fruit and vegetable servings and accrued 150 minutes or more per week of activity were more successful at weight loss maintenance.

The study authors concluded that the behavioral strategy of reducing consumption of fast foods could assist people in maintaining weight loss. Furthermore, the combined approach of consuming five or more fruit and vegetable servings per day and attaining 150 minutes or more per week of physical activity was a common strategy among adults successful at weight loss maintenance.

Assessment of weight involves evaluating body mass index, waist circumference and the patient's risk factors.

Many factors, including an individual's age, gender and height, are considered to determine if he/she is overweight. People increase in weight until they are fully grown. On average, females tend to gain about 16 pounds of body weight from age 25-54. In contrast, males tend to gain about 10 pounds of body weight from age 25-45. By around age 55, both men and women start to decline in weight. Females naturally have more body fat and less muscles mass than men. It is also normal for taller individuals to weigh more than shorter individuals.

Obesity is typically considered a long-term condition that often persists for many years. Researchers believe that many factors, including poor diet, overeating, pregnancy, medications, medical conditions, genetics, gender and age, may contribute to a person becoming obese.

Obesity can have serious long-term effects on health. Individuals who are overweight have an increased risk of developing many life-threatening illnesses, including heart disease, high blood pressure, stroke, obesity, diabetes, osteoporosis and cancer. According to the American Heart Association, obesity was associated with nearly 112,000 deaths in 2005.

In the United States, obesity is considered an epidemic. More than half of all Americans are considered overweight, and about 20 percent of children are overweight.

For more information on integrative weight loss approaches, please visit Natural Standard's Comparative Effectiveness database.

Integrated Breathing and Relaxation Training for Asthma

Asthmainhaler An integrated breathing and relaxation technique may help ease the symptoms associated with asthma, a new study reports.

Asthma is a chronic, inflammatory lung disease. The air passages within the lungs are constantly swollen, restricting the amount of air allowed to pass through the trachea. Asthmatics have recurrent breathing problems and a tendency to cough and wheeze.

According to the American Lung association, about 20 million Americans have asthma, which causes about 5,000 deaths each year. Asthma is incurable, but many medications and changes in behavior may help manage the condition.

Researchers from London, England, explained that an integrated breathing and relaxation technique known as the Papworth method has been implemented by physiotherapists since the 1960s for patients with asthma and dysfunctional breathing.

The study analyzed the effectiveness of the Papworth method in 85 patients (36 men) who were randomized to the control group (46 patients) or to the intervention group receiving five sessions of treatment by the Papworth method (39 patients). Both groups received usual medical care. Assessments were undertaken at baseline, post-treatment (six months after baseline) and at 12 months.

The study found that symptoms were slightly relieved in the intervention group; however, the groups did not differ significantly following the treatment on objective measures of respiratory function except for relaxed breathing rate.

The study authors concluded that the Papworth method appears to relieve respiratory symptoms, dysfunctional breathing and adverse mood compared with usual care. The authors suggested that further controlled trials are warranted to confirm this finding, assess the effect in other patient groups and determine whether there is some effect on objective measures of respiratory function.

Integrative therapies with good scientific evidence in the treatment of asthma include boswellia, choline, coleus, psychotherapy, Pycnogenol® and yoga.

For more information on asthma, please visit Natural Standard's Medical Conditions or Allergy & Immunology database. For more information on the therapies mentioned in this article, please visit Natural Standard's Foods, Herbs & Supplements database.

Faith and Family Caregiving

Prayercom Faith in God and belonging to a religion may reduce stress and anxiety in family caregivers, a new study suggests.

Researchers from Stanford University examined the impact of prayer, faith and religion on the well-being of individuals who serve as caregivers to a family member.

It has been suggested that patients who pray for themselves or are aware that others are praying for them may develop stronger coping skills and decreased anxiety, thereby potentially improving health outcomes. Other theories include beneficial effects of prayer or "positive thinking" on the immune system, central nervous system (brain) or hormonal system. The meditative, relaxing effects of prayer have been suggested to have beneficial effects such as lowering blood pressure. There are no plausible scientific explanations for the possible effects of intercessory prayers said without the knowledge of patients.

The study, conducted over a 14-month period, used participant observation and in-depth interviews to evaluate the health of African American adults providing in-home care for a family member with chronic confusion.

The majority of caregivers were adult daughters. Nearly half attributed chronic confusion to a difficult life and emotional stress or "worry;" a third believed it to be a natural component of "old age." The study reported that caregivers tended to view their work as an expression of love and devotion that was accompanied by emotional stress and personal sacrifice. While just under half of the caregivers had no other family members willing or available to assist with the physical care of the elder, the majority were able to turn to family members for emotional support.

The study found that caregivers identified strong religious beliefs as the primary force that sustain